Ginger Snaps Back: The Beginning (2004)

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Sisters Brigitte and Ginger find themselves stuck in the wilderness of 19th century Canada. They find refuge in a traders’ fort, where they're surrounded by an eclectic group of near insane explorers and traders. The girls’ sanctuary turns terrifying when the fort comes under attack by savage werewolves. A mysterious Indian hunter may be the girls’ only hope against the beasts, but complications ensue when one of the girls is bitten by a werewolf.