Cast and credits of 500 Keys

Dan Castellaneta
Homer Simpson / Wiseguy / Guy with a letter / Barney Gumble / Gil Gunderson / Mayor Quimby / Key Man (voice)

Julie Kavner
Marge Simpson (voice)

Nancy Cartwright
Bart Simpson / Todd Flanders / Nelson Muntz / Ralph Wiggum / Joe Spuckler (voice)

Yeardley Smith
Lisa Simpson (voice)

Hank Azaria
German Biker / Chief Clancy Wiggum / Kirk Van Houten / Professor Frink / Duffman / Irritable Bowel Syndrome Support Group Man / Superintendent Chalmers / Cle

Harry Shearer
Ned Flanders / Dr. Hibbert / Reverend Lovejoy / Principal Seymour Skinner / Otto Mann (voice)

Albert Brooks
Hank Scorpio (voice) (as A. Brooks)

Chris Edgerly
Additional Voices (voice)

Pamela Hayden
Milhouse Van Houten / Rod Flanders (voice)

Tress MacNeille
Irritable Bowel Syndrome Support Group Woman / Nancy Drew / Brandine Spuckler / Mary Anne / Agnes Skinner (voice)