Wristcutters: A Love Story is a little fantasy/road-trip adventure with a story akin, but not too similar, to The Wizard of Oz, set in an afterlife reserved for only those who kill themselves. I found it a charming piece of work, and I was pleasantly surprised by the appearance of Tom Waits and the use of Gogol Bordello's music as piece of the background story. The use of generally unknown/less-known actors works very nicely and I found the performances of each rather well done. True, the story is a tad predictable most of the time. But this isn't really too much of an issue for me as the film is carried out very well overall and I think it actually helps the simplicity of the work as a whole to not try to surprise the viewers with something that just wouldn't fit.
One last thing though: Keep in mind that you really need to view this as a fantasy work (like The Wizard of Oz) rather than a religious concept of a form of purgatory, as this helps to get the mood of the film right. Its actually rather light-hearted for being a film about suicide. ;) Enjoy.