Louisa Gavin

Louisa Gavin is a fictional character from the 2026 FOX comedy-drama series Best Medicine, portrayed by Abigail Spencer. Louisa is a schoolteacher in the small coastal community of Port Wenn, Maine. She is introduced as one of the local residents who questions Dr. Martin Best's blunt and abrasive manner after he arrives in town to practice medicine.

Louisa is closely connected to the Port Wenn community and becomes an important person in Martin's life as their relationship develops throughout the series.

Character: Louisa Gavin
Portrayed by: Abigail Spencer
TV Series: Best Medicine
Year: 2026–present
Occupation: Schoolteacher
Residence: Port Wenn, Maine, USA
Gender: Female
Relationship Status: Complicated / Romantic relationship with Dr. Martin Best
Former Fiancé: Sheriff Mark Mylow