Dante

Dante (ダンテ, Dante) is the central antagonist of the Fullmetal Alchemist 2003 anime series, and is first introduced in Episode 32. She is a cold elderly woman and a formidable alchemist herself. Posing as the master and the benefactor of the Homunculi, Dante is responsible for setting in motion the events of the series and the challenges its protagonists must face along the way, and orchestrates her agenda within the shadows of the Amestrian government and military.