Animaniacs

The 100 Greatest Cartoon Characters of all Time (100 items)
list by Michael S

American Pop Icons (1184 items)
list by moviebuff

Yakko, Wakko, and Dot %u2013 the "Warner Brothers (and the Warner Sister)", voiced by Rob Paulsen, Jess Harnell, and Tress MacNeille. Yakko (the oldest) is a fast-talking smart alec, reminiscent at times of Groucho Marx. Wakko (the middle child) has a huge appetite, a gag bag filled with tricks and often has his tongue sticking out (and a scouse accent modeled by Harnell after a younger John Lennon), and Dot (the youngest) is cute and sassy, and uses her apparent innocence to manipulate and torment those who stand in her way as well as chasing Leading Men from Hollywood (like Mel Gibson) around. The Warners often appear in other characters' skits, usually being chased by Ralph the security guard; most other characters are confined to their own segments.