Franken Fran, Bd. 1

Fran is a girl created by the world's top biologist. She takes care of her creator's mansion while he is away on research. Her life is pretty uneventful, until many different medical cases begin falling in her lap. This manga is very graphic and frequently features scenes of extreme gore, as Fran begins to do more and more intense surgical procedures. There is a fair amount of black humor, as usually each story ends up with Fran having created some sort of gruesome monstrosity from her patients, while in the end answering to their requests - sometimes literally.