I hear a lot of mixed reviews about this over the internet. Some have said it's way better than Family Guy, Some say it's sub par to Family Guy, and some just say it's just as bad as Family Guy.
I believe this is just as good as family guy. No worse. No better. There are some better episodes of Family Guy and there are some better episodes of American Dad. I've watched Family Guy first, so I'm not being biased. The Cleaveland show on the other hand wasn't nearly as good.
It's a matter of preference. In a lot of ways this is very similar to family guy. Dumb husband, hot wife, misunderstood teenage girl, nerdy dunce son. The only big difference is the Alien and the Fish vs. the baby and the dog.