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First show to end it's run as the #1 show on TV, first to film in front of a live audience and Desi Arnaz is first hispanic on Network TV.
Strangely, the first to show a toilet, which had been taboo until then.
First successful American Soap.
First animated series made for prime time TV and first series to discuss infertility.
First TV show to have a black main character.
First interracial kiss and first time "Hell" is said on network tv.
First "God damn it" and first gay character.
First show where the main character has an abortion.
First deliberate time male nudity, from behind, is shown.
First accidental glimpse of a man's "package"
First kiss shared between 2 females, although only one of them was gay.
First openly gay actor playing an openly gay character. She also was the first to come out on TV.
First openly gay teenager.
First Romantic kiss between 2 men on primetime TV.