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Dan Aykroyd not only has webbed toes (that he shows off in the video), but also has heterochromia, a defect that causes two different colored irises.
Jennifer Garner has an overlapping toe on her right foot.
Megan Fox has infamously stubby clubbed thumbs, or brachydactyly thumbs.
The lead singer of Smashing Pumpkins has a condition known as Klippel-Trenauney syndrome, commonly known as a port-wine stain birthmark, on the palm of his left hand.
Hrithik Roshan has two thumbs on his right hand.
Andy Garcia was born with a conjoined twin on his shoulder, which was surgically removed when he was a toddler.
Lily Allen famously has a third nipple, which she gladly shows off at the end of the video above.
Other famous stars with third nipples are Carrie Underwood, Tilda Swinton and Mark Wahlberg.
Matthew Perry is missing the tip of his middle finger on his right hand.
The pockmarked scarring on Seal's face are from a skin condition known as discoid lupus erythematosus.
Denzel Washington broke his finger and never had it corrected.
Joaquin Pheonix's strange lip scar is from a microform cleft, a mild form of a cleft lip that develops during gestation. Many think he was born with a cleft lip and the scar is the result of corrective surgery, which is false.
Kate Bosworth has heterochromia, or two different colored eyes.
Mila Kunis also has heterochromia.
Unlike the last celebrities, David Bowie does not technically have heterochromia. He was in a fight as a teenager and when he was punched in the eye, his pupil was permanently dialated, giving the appearance of two different colored eyes.
Tina Fey has a scar on her cheek due to a strange incident when she was five. She was in her front yard when, without any warning or reason, a stranger violently cut her cheek.
Vince Vaughn's "penis thumb" is from a car accident when he was 17 that severed the tip of his right thumb.