The Corrections: A Novel - Jonathan Franzen

All five members of the Lambert family get their due, as everybody's lives swirl out of control. Paterfamilias Alfred is slipping into dementia, even as one of his inventions inspires a pharmaceutical giant to revolutionize treatment of his disease. His stubborn wife, Enid, specializes in denial; so do their kids, each in an idiosyncratic way. Their hepcat son, Chip, lost a college sinecure by seducing a student, and his new career as a screenwriter is in peril. Chip's sister, Denise, is a chic chef perpetually in hot water, romantically speaking; banker brother Gary wonders if his stifling marriage is driving him nuts. We inhabit these troubled minds in turn, sinking into sorrow punctuated by laughter, reveling in Franzen's satirical eye:

Gary in recent years had observed, with plate tectonically cumulative anxiety, that population was continuing to flow out of the Midwest and toward the cooler coasts.... Gary wished that all further migration [could] be banned and all Midwesterners encouraged to revert to eating pasty foods and wearing dowdy clothes and playing board games, in order that a strategic national reserve of cluelessness might be maintained, a wilderness of taste which would enable people of privilege, like himself, to feel extremely civilized in perpetuity.